https://doi.org/10.4081/monaldi.2025.3336
Impact of patient counseling on medication adherence in respiratory tract infection patients in a tertiary care teaching hospital
Submitted: January 6, 2025
Accepted: February 17, 2025
Published: April 23, 2025
Accepted: February 17, 2025
Abstract Views: 246
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Respiratory tract infections (RTIs) significantly impact public health in India, with high morbidity and mortality rates. Effective management of RTIs relies on medication adherence (MA), which is often challenged by factors like forgetfulness, side effects, and socioeconomic barriers. This study aimed to evaluate the impact of patient counseling on MA among RTI patients and to assess the influence of demographic, socioeconomic, and clinical factors on adherence. A cross-sectional observational study was conducted at Vivekananda General Hospital Hubballi, India, from August 2023 to January 2024, involving 200 RTI patients. MA was measured using the Medication Adherence Report Scale (MARS) before and after patient counseling. Statistical analysis assessed the effect of age, gender, comorbidities, and socioeconomic status on adherence. MA significantly improved following patient counseling, with mean MARS scores increasing from 4.13±1.601 to 6.80±1.592 (p<0.05). Age was positively correlated with adherence, while factors like gender, infection type, and socioeconomic status had varied effects. Overall, patient counseling effectively enhanced adherence across all groups. The study underscores the importance of patient counseling in improving MA among RTI patients. Personalized interventions and addressing socioeconomic barriers are crucial for optimizing treatment outcomes.
Mirzayev F, Viney K, Linh NN, et al. World Health Organization recommendations on the treatment of drug-resistant tuberculosis, 2020 update. Eur Respir J 2021;57:2003300.
DOI: https://doi.org/10.1183/13993003.03300-2020
India State-Level Disease Burden Initiative Collaborators. Nations within a nation: variations in epidemiological transition across the states of India, 1990-2016 in the Global Burden of Disease Study. Lancet 2017;390:2437-60.
GBD 2016 DALYs and HALE Collaborators. Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet 2017;390:1260-344.
DOI: https://doi.org/10.1016/S0140-6736(17)32130-X
Salvi S, Apte K. The burden of chronic respiratory diseases and their heterogeneity across the states of India: the Global Burden of Disease Study 1990-2016. Lancet Glob Health 2018;6:e1363-74.
Vrijens B, De Geest S, Hughes DA, et al. A new taxonomy for describing and defining adherence to medications. Br J Clin Pharmacol 2012;73:691-705.
DOI: https://doi.org/10.1111/j.1365-2125.2012.04167.x
Osterberg L, Blaschke T. Adherence to medication. N Engl J Med 2005;353:487-97.
DOI: https://doi.org/10.1056/NEJMra050100
Brown MT, Bussell JK. Medication adherence: WHO cares? Mayo Clin Proc 2011;86:304-14.
DOI: https://doi.org/10.4065/mcp.2010.0575
Goldman DP, Joyce GF, Zheng Y. Prescription drug cost sharing: associations with medication and medical utilization and spending and health. JAMA 2007;298:61-9.
DOI: https://doi.org/10.1001/jama.298.1.61
Nguyen TMU, La Caze A, Cottrell N. What are validated self-report adherence scales really measuring? A systematic review. Br J Clin Pharmacol 2014;77:427-45.
DOI: https://doi.org/10.1111/bcp.12194
Chan AHY, Horne R, Hankins M, et al. The Medication Adherence Report Scale: a measurement tool for eliciting patients' reports of nonadherence. Br J Clin Pharmacol 2020;86:1281-8.
DOI: https://doi.org/10.1111/bcp.14193
Anand R, Kharbanda S. Health-related quality of life in patients with chronic obstructive pulmonary disease: a hospital-based study. Indian J Med Res 2021;153:459-64.
DOI: https://doi.org/10.4103/ijmr.IJMR_1812_18
Branche AR, Falsey AR. Respiratory syncytial virus infection in older adults: an under-recognized problem. Drugs Aging 2015;32:261-9.
DOI: https://doi.org/10.1007/s40266-015-0258-9
Abdel-Aziz HR, Atia NS. Respiratory infections prevention in rural older adults: an interventional study. Clin Nurs Res 2022;31:1445-53.
DOI: https://doi.org/10.1177/10547738221081981
Eagan TML, Gulsvik A, Eide GE. The effect of educational level on the incidence of asthma and respiratory symptoms. Respir Med 2004;98:730-6.
DOI: https://doi.org/10.1016/j.rmed.2004.02.008
Dickie HA, Rankin J. Farmer’s lung: An acute granulomatous interstitial pneumonitis occurring in agricultural workers. J Am Med Assoc 1958;167:1069-76.
DOI: https://doi.org/10.1001/jama.1958.02990260011004
Ejaz H, Alsrhani A, Zafar A, et al. COVID-19 and comorbidities: deleterious impact on infected patients. J Infect Public Health 2020;13:1833-9.
DOI: https://doi.org/10.1016/j.jiph.2020.07.014
Gaffney AW, Himmelstein DU, Christiani DC, Woolhandler S. Socioeconomic inequality in respiratory health in the US from 1959 to 2018. JAMA Intern Med 2021;181:968-76.
DOI: https://doi.org/10.1001/jamainternmed.2021.2441
Jaakkola MS, Lajunen TK, Rantala AK, et al. Occupation and occurrence of respiratory infections among adults with newly diagnosed asthma. BMC Pulm Med 2023;23:140.
DOI: https://doi.org/10.1186/s12890-023-02413-8
Lieberman D, Lieberman D, Korsonsky I, et al. A comparative study of the etiology of adult upper and lower respiratory tract infections in the community. Diagn Microbiol Infect Dis 2002;42:21-8.
DOI: https://doi.org/10.1016/S0732-8893(01)00324-8
Jimmy B, Jose J. Patient medication adherence: measures in daily practice. Oman Med J 2011;26:155-9.
DOI: https://doi.org/10.5001/omj.2011.38
Gellad WF, Grenard JL, Marcum ZA. A systematic review of barriers to medication adherence in the elderly: looking beyond cost and regimen complexity. Am J Geriatr Pharmacother 2011;9:11-23.
DOI: https://doi.org/10.1016/j.amjopharm.2011.02.004
Edworthy SM, Devins GM. Improving medication adherence through patient education: distinguishing between appropriate and inappropriate utilization. J Rheumatol 1999;26:1793-801.
Conn VS, Ruppar TM, Enriquez M, Cooper PS. Patient-centered outcomes of medication adherence interventions: systematic review and meta-analysis. Value Health 2016;19:277-85.
DOI: https://doi.org/10.1016/j.jval.2015.12.001
Tolley A, Hassan R, Sanghera R, et al. Interventions to promote medication adherence for chronic diseases in India: a systematic review. Front Public Health 2023;11:1194919.
DOI: https://doi.org/10.3389/fpubh.2023.1194919
Su Y, Wang X, Cai B, et al. The analysis of factors affecting medication adherence in patients with myasthenia gravis: a cross-sectional study. Ther Adv Neurol Disord 2023;16:175628642312060.
DOI: https://doi.org/10.1177/17562864231206877
Wang C, Liu K, Sun X, Yin YH, Tang T. Effectiveness of motivational interviewing among patients with COPD: a systematic review with meta-analysis and trial sequential analysis of randomized controlled trials. Patient Educ Couns 2022;105:3174-85.
DOI: https://doi.org/10.1016/j.pec.2022.07.019
Silva Almodóvar A, Nahata MC. Medication adherence in Medicare-enrolled older adults with chronic obstructive pulmonary disease before and during the COVID-19 pandemic. J Clin Med 2022;11:6985.
DOI: https://doi.org/10.3390/jcm11236985
Mahmoodi H, Jalalizad Nahand F, Shaghaghi A, et al. Gender-based cognitive determinants of medication adherence in older adults with chronic conditions. Patient Prefer Adherence 2019;13:1733-44.
DOI: https://doi.org/10.2147/PPA.S219193
Franssen FME, Rochester CL. Comorbidities in patients with COPD and pulmonary rehabilitation: do they matter? Eur Respir Rev 2014;23:131-41.
DOI: https://doi.org/10.1183/09059180.00007613
Homętowska H, Świątoniowska-Lonc N, Klekowski J, et al. Treatment adherence in patients with obstructive pulmonary diseases. Int J Environ Res Public Health 2022;19:11573.
DOI: https://doi.org/10.3390/ijerph191811573
Ali MM, Taha MM, Ahmed AE, et al. Psychotropic medication adherence and its associated factors among schizophrenia patients: exploring the consistency of adherence scales. Cureus 2023;15:e46118.
DOI: https://doi.org/10.7759/cureus.46118
Nagamine Y, Shobugawa Y, Sasaki Y, et al. Associations between socioeconomic status and adherence to hypertension treatment among older adults in urban and rural areas in Myanmar: a cross-sectional study using baseline data from the JAGES in Myanmar prospective cohort study. BMJ Open 2023;13:e065370.
DOI: https://doi.org/10.1136/bmjopen-2022-065370
Khan FU, Fang Y. Effectiveness of pharmacist-led brief educational intervention for adherence to the antibiotics for lower respiratory tract infections (EATSA) in post-conflict rural areas of Pakistan: study protocol for a randomized controlled trial. Antibiotics 2021;10:1147.
DOI: https://doi.org/10.3390/antibiotics10101147
Dong Y-H, Choudhry NK, Krumme AK et al. Impact of hospitalization on medication adherence estimation in claims data. J Clin Pharm Ther 2017;42:318-28.
DOI: https://doi.org/10.1111/jcpt.12517
Ethics Approval
The KLE College of Pharmacy Ethical Committee gave its approval to the study (IEC Reference Number: KLECOPH/IEC/2023-24/08).How to Cite
Chitralu, Sai Phalguna Prakash, Princy Domnic Dsouza, Chandrashekhar Mallikarjun Patil, Sanatkumar Bharamu Nyamagoud, Vinod Ashok Koujalagi, and Agadi Hiremath Viswanatha Swamy. 2025. “Impact of Patient Counseling on Medication Adherence in Respiratory Tract Infection Patients in a Tertiary Care Teaching Hospital”. Monaldi Archives for Chest Disease, April. https://doi.org/10.4081/monaldi.2025.3336.
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