https://doi.org/10.4081/monaldi.2022.2333

Acute and long-term management of severe bronchiectasis with high flow nasal therapy: a case report

Vol. 93 No. 2 (2023)
Submitted: May 20, 2022
Accepted: August 1, 2022
Published: August 4, 2022
Bronchiectasis, exacerbation, high flow nasal therapy, high flow nasal oxygen, HFNT, HFNO, acute, long-term, domiciliary
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Authors

Pietro Impellizzeri
Department of Clinical and Experimental Medicine, University of Catania, Italy.
Santi Nolasco
https://orcid.org/0000-0003-3995-7662
Department of Clinical and Experimental Medicine, University of Catania, Italy.
Raffaele Campisi
Respiratory Medicine Unit, Policlinico “G. Rodolico - San Marco” University Hospital, Catania, Italy.
Antonino Cipolla
https://orcid.org/0000-0003-0494-1644
Department of Clinical and Experimental Medicine, University of Catania, Italy.
Alba Borgese
Department of Clinical and Experimental Medicine, University of Catania, Italy.
Stefano Alia
https://orcid.org/0000-0002-7848-862X
Respiratory Medicine Unit, Policlinico “G. Rodolico - San Marco” University Hospital, Catania, Italy, Italy.
Nunzio Crimi
Department of Clinical and Experimental Medicine, University of Catania, Italy.
Claudia Crimi
dott.claudiacrimi@gmail.com
https://orcid.org/0000-0002-9088-5214
Respiratory Medicine Unit, Policlinico “G. Rodolico - San Marco” University Hospital, Catania, Italy.

Bronchiectasis (BE) is a long-term, chronic lung condition featured by widened and scarred airways. These can alter the physiological mucociliary clearance, making it difficult to clear mucus and microorganisms, leading to frequent exacerbations. High flow nasal therapy (HFNT) is a noninvasive respiratory support that delivers heated and humidified gas eventually enriched with oxygen, through a nasal cannula.  Humidification is crucial for adequate airways mucociliary clearance, improving ciliary function and consequently reducing airways inflammation and recurrent infections. HFNT has been mostly used in patients with acute hypoxemic respiratory failure and in selected patients with chronic respiratory failure due to COPD. Still, evidence about its use in acute and long-term home setting in patients with clinically relevant BE are lacking. We report a case of severe widespread BE, already on top medical therapy and pulmonary rehabilitation, still suffering from difficult mucus expectoration and recurrent exacerbations, who has been additionally treated with HFNT, both in hospital and domiciliary, reporting significant improvements on relevant clinical and patient-centered outcomes. Thus, HFNT may confer additional benefits as an add-on treatment of patients with severe BE and respiratory failure.

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How to Cite

Impellizzeri, Pietro, Santi Nolasco, Raffaele Campisi, Antonino Cipolla, Alba Borgese, Stefano Alia, Nunzio Crimi, and Claudia Crimi. 2022. “Acute and Long-Term Management of Severe Bronchiectasis With High Flow Nasal Therapy: A Case Report”. Monaldi Archives for Chest Disease 93 (2). https://doi.org/10.4081/monaldi.2022.2333.
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