Clinico-epidemiological profile of COVID-19 patients admitted during third wave of pandemic in a tertiary care hospital in New Delhi, India

Submitted: May 12, 2022
Accepted: August 11, 2022
Published: September 5, 2022
Abstract Views: 773
PDF: 248
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Even nearly two years after the first reported case, the novel coronavirus (SARS-CoV-2) continues to ebb and flow around the world. A retrospective cohort study was carried out to determine the clinico-epidemiological profile and outcome of the cases. The study analyzed secondary data from 827 patients who presented to our center with COVID-19-related illnesses between December 15, 2021, and February 15, 2022 (third wave in India). There was a significant difference in the vaccination status of patients treated at home and those admitted, with 87.9% having received two doses compared to 74% in the second group being unvaccinated. Patients who were isolated at home recovered at a rate of 99.4%, while hospitalized patients died at a rate of 26.5%. Vaccination reduces the severity of COVID-19; however, constant vigilance for new variants, precautionary measures, and increased vaccination drives are critical moving forward.


*Other members of the Safdarjung Hospital COVID-19 working group: B. Lal (Medicine), Harish Sachdeva (Anaesthesiology), Santvana Kohli (Anaesthesiology), Amandeep Jaswal (Anaesthesiology), Sumitra Bachani (Obstetrics and Gynecology), Ajay Kumar (Pediatrics), Rohit Kumar (Pulmonary Medicine), Vidya Sagar Chaturvedi (Surgery), Vinod Chaitanya (Medicine).



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Citations [Internet]. Where did Omicron come from? Three key theories. Accessed March 25, 2021.Available from:
Li L, Huang T, Wang Y, et al. COVID-19 patients' clinical characteristics, discharge rate, and fatality rate of meta-analysis. J Med Virol 2020;92:577-83. DOI:
Picon RV, Carreno I, da Silva AA, et al. Coronavirus disease 2019 population-based prevalence, risk factors, hospitalization, and fatality rates in southern Brazil. Int J Infect Dis 2020;100:402-40. DOI:
Government of Delhi, Department of Information & Publicity. Delhi fights Corona. Bulletin. Accessed March 25, 2021. Available from:
Government of NCT of Delhi. Guide to home isolation. Accessed March 25, 2021. Available from:
Indian Council of Medical Research. Advisory on purposive testing strategy for COVID-19 in India (Version VII, dated January 10, 2022). Accessed March 25, 2021. Available from:
World Health Organization. Statement on Omicron sublineage B.A.2. Accessed March 25, 2021. Available from:
Maslo C, Friedland R, Toubkin M, et al. Characteristics and outcomes of hospitalized patients in South Africa during the COVID-19 Omicron wave compared with previous waves. JAMA 2022;327:58384. DOI:
Abdullah F, Myers J, Basu D, et al. Decreased severity of disease during the first global omicron variant covid-19 outbreak in a large hospital in Tshwane, South Africa. Int J Infect Dis 2022;116:38-42. DOI:
Iuliano AD, Brunkard JM, Boehmer TK, et al. Trends in disease severity and health care utilization during the early Omicron variant period compared with previous SARS-CoV-2 high transmission periods - United States, December 2020-January 2022. MMWR Morb Mortal Wkly Rep 2022;71:146-152. DOI:
Das S, Kar SS, Samanta S, et al. Immunogenic and reactogenic efficacy of Covaxin and Covishield: a comparative review. Immunol Res 2022;70:289-315. DOI:
Parikh PM, Maheshwari U, Krishna VM, et al. Robust protective effect of COVID-19 vaccination in India-Results of Survey in the midst of pandemic's second wave. South Asian J Cancer 2021;10:28-31. DOI:
Bharat Biotech [Internet]. COVAXIN® (BBV152) Booster shown to neutralize both Omicron and Delta variants of SARS-CoV-2. Accessed March 25, 2021. Available from:
Buchan SA, Chung H, Brown KA, et al. Effectiveness of COVID-19 vaccines against Omicron or Delta symptomatic infection and severe outcomes. medRxiv 2021.12.30.21268565. DOI:

Ethics Approval

Institutional Ethical Committee approval obtained for the study (IEC/VMMC/SJH/Project/2021-03/CC-136)

How to Cite

Agrawal, Shreyash, Ravindra Nath, Pranav Ish, Neeraj Kumar Gupta, Rajni Gaind, Suniti Kale, Rani Gera, Anjali Dabral, Nitesh Gupta, and *Other members of the Safdarjung Hospital COVID 2019 working group. 2022. “Clinico-Epidemiological Profile of COVID-19 Patients Admitted During Third Wave of Pandemic in a Tertiary Care Hospital in New Delhi, India”. Monaldi Archives for Chest Disease 93 (2).