Rhythm-control vs rate-control in the elderly: When to do it and which drug to prefer?

Submitted: April 24, 2018
Accepted: May 14, 2018
Published: June 7, 2018
Abstract Views: 3402
PDF: 640
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Atrial fibrillation (AF) is a relevant cardiovascular condition that is more prevalent in the elderly patients aged over 65 years. AF, with abnormal rate and rhythm can cause symptoms directly or indirectly by exacerbating other frequently coexisting cardiac conditions such as valvular heart disease, hypertension, ischemic cardiomyopathy, dilated cardiomyopathy, and hypertrophic cardiomyopathy. Evidence suggests that aging-related cardiovascular changes predispose to the elderly to AF. Current therapeutic options such as antiarrhythmic drugs have not been extensively evaluated in the elderly population. Emerging pharmacological and non-pharmacological treatment options for the management of AF, such as dronedarone or catheter ablation, are of particular interest in the elderly. The present paper reviews the pathophysiology, diagnosis, and the management of AF in the elderly patient.

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Botto, Giovanni Luca, Carlo Piemontese, and Giovanni Russo. 2018. “Rhythm-Control Vs Rate-Control in the Elderly: When to Do It and Which Drug to Prefer?”. Monaldi Archives for Chest Disease 88 (2). https://doi.org/10.4081/monaldi.2018.949.