Multum non multa: airway distensibility by forced oscillations

Submitted: May 31, 2016
Accepted: May 31, 2016
Published: June 22, 2016
Abstract Views: 992
PDF: 452
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Authors

Airway distensibility although appears to be unaffected by airway smooth muscle tone probably related to airway remodelling, after bronchodilator treatment is significantly increased in subjects with asthma. We assessed airway distensibity and its first moment derivative in two patients with mild intermittent asthma and normal spirometry. The increase in airway distensibility after bronchodilation measured at the tidal volume range during quiet breathing by forced oscillations was not accompanied by a change in its first moment, while the latter showed a significant increase in a second patient after anti-inflammatory treatment. It appears that airway distensibility is sensitive to reduction of bronchial smooth muscle tone after bronchodilation, but in addition its first moment might provide information on a change of both bronchial smooth muscle tone and small airways inflammation.

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Mermigkis, Charalampos, Sophia E. Schiza, and Panagiotis Panagou. 2016. “Multum Non Multa: Airway Distensibility by Forced Oscillations”. Monaldi Archives for Chest Disease 81 (1-2). https://doi.org/10.4081/monaldi.2015.746.