Pneumology - Original Articles

Clinical outcomes of rigid bronchoscopic airway interventions: insights from an Indian tertiary care center

Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Published: 21 April 2026
14
Views
21
Downloads

Authors

Rigid bronchoscopy (RB) forms an indispensable part of the interventional bronchoscopist’s skills, allowing the performance of complex airway interventions for a variety of benign and malignant airway disorders. Experiential data on the procedure is limited, particularly in adults. We conducted a retrospective analysis of medical records from 82 adult patients who underwent RB at our center. The primary objective was to evaluate the clinical indications, procedural outcomes, complication rates, and overall efficacy of RB in this cohort. Collected data included patient demographics, presenting symptoms, etiological diagnoses, and anesthesia-related parameters such as induction agents, maintenance protocols, sedation strategies, and the use of neuromuscular blockade. Post-procedural outcomes and follow-up mortality were also assessed. The mean patient age was 56.2±12.6 years, with 71.9% males. Common symptoms were cough (90.2%) and dyspnea (82.9%). Malignancies accounted for 90.2% of cases, with lung cancer being the most prevalent (68.2%). RB was primarily performed for stenting (63.4%) and tumor debulking (29.2%). Total intravenous anesthesia was used in 92.6%, with mean induction and reversal times of 75.3±4.3 seconds and 10.69±2.4 minutes, respectively. Minor complications occurred in 29.3% (bleeding 29.3%, bronchospasm 17.1%, and hypoxia 13.4%) and major complications in 2.4%. After the procedure, immediate extubation was achieved in 49 patients (59.8%), while 24 (29.3%) required short-term ventilator support (<24 h) and 9 (11.0%) required prolonged support (>24 h). The median hospital stay was 7 days (interquartile range 5-11). Symptomatic improvement at discharge was observed in 72/82 patients (87.8%). In-hospital mortality was 6.1% (5/82), mainly due to severe infections (hospital-acquired or ventilator-associated pneumonia) or massive endobronchial bleeding. Among patients with available follow-up (n=52), 3-month mortality was 11.5% (n=6). In this real-world cohort, RB demonstrated a high success rate with minimal complications, reinforcing its role as a critical tool in managing complex airway conditions. The procedure demonstrated high efficacy, particularly in malignant cases, with acceptable complication rates. Dedicated training is essential to enhance experience, gain expertise, and ensure optimal outcomes while minimizing procedural risks.

Downloads

Download data is not yet available.

Citations

Ernst A, Feller-Kopman D, Becker HD, Mehta AC. Central airway obstruction. Am J Respir Crit Care Med 2004;169:1278-97.
Cavaliere S, Venuta F, Foccoli P, et al. Endoscopic treatment of malignant airway obstructions in 2,008 patients. Chest 1996;110:1536-42.
Siegel RL, Miller KD, Jemal A. Cancer statistics, 2020. CA Cancer J Clin 2020;70:7-30.
Aravena C, Mehta AC, Almeida FA, et al. Innovation in rigid bronchoscopy—past, present, and future. J Thorac Dis 2023;15:2836-47.
Grillo HC, Donahue DM, Mathisen DJ, et al. Postintubation tracheal stenosis: treatment and results. J Thorac Cardiovasc Surg 1995;109:486-92.
Prakash UB, Offord KP, Stubbs SE. Bronchoscopy in North America: the ACCP survey. Chest 1991;100:1668-75.
Ost DE, Ernst A, Grosu HB, et al. Complications following therapeutic bronchoscopy for malignant central airway obstruction. Chest 2015;148:450-71.
Guibert N, Roy P, Amari L, et al. Therapeutic bronchoscopy for malignant central airway obstruction: introduction to the EpiGETIF registry. Respirology 2024;29:505-12.
Mishra J, Acharya S, Taksande AB, et al. Occupational risks and chronic obstructive pulmonary disease in the Indian subcontinent: a critical review. Cureus 2023;15:e41149.
Global Action to End Smoking. India | Tobacco and health around the world. Available from: https://globalactiontoendsmoking.org/research/tobacco-around-the-world/india/
Madan K, Shankar SH, Mittal S, et al. A survey of rigid bronchoscopy practices in India. Lung India 2024;41:482-6.
Ivanick NM, Kunadharaju R, Bhura S, et al. Epidemiology and survival of malignant central airway obstruction in lung cancer identified on cross-sectional imaging. J Bronchol Interv Pulmonol 2024;31:e0970.
Madan K, Agarwal R, Aggarwal AN, Gupta D. Therapeutic rigid bronchoscopy at a tertiary care center in North India: initial experience and systematic review of Indian literature. Lung India 2014;31:9-15.
Sathishkumar K, Chaturvedi M, Das P, et al. Cancer incidence estimates for 2022 and projection for 2025: results from National Cancer Registry Programme, India. Indian J Med Res 2022;156:598-607.
Ost DE, Ernst A, Grosu HB, et al. Therapeutic bronchoscopy for malignant central airway obstruction. Chest 2015;147:1282-98.
Dumon JF. A dedicated tracheobronchial stent. Chest 1990;97:328-32.
Shin B, Chang B, Kim H, Jeong BH. Interventional bronchoscopy in malignant central airway obstruction by extra-pulmonary malignancy. BMC Pulm Med 2018;18:46.
Drummond M, Magalhães A, Hespanhol V, Marques A. Rigid bronchoscopy: complications in a university hospital. J Bronchol Interv Pulmonol 2003;10:177-82.
Freitas C, Serino M, Cardoso C, et al. Predictors of survival and technical success of bronchoscopic interventions in malignant airway obstruction. J Thorac Dis 2021;13:6760-8.
Grosu HB, Eapen GA, Morice RC, et al. Stents are associated with increased risk of respiratory infections in patients undergoing airway interventions for malignant airway disease. Chest 2013;144:441-9.
SGRH Hospital. The rising threat: lung cancer in India. 2024. Available from: https://sgrh.com/blog/the-rising-threat-lung-cancer-in-india

Ethics Approval

The study was approved by the Institutional Ethics Committee of the All India Institute of Medical Sciences, Rishikesh (approval no. AIIMS/IEC/24/575 dated October 11, 2024). Consent to participation was waived due to the retrospective design of the study.

How to Cite



“Clinical Outcomes of Rigid Bronchoscopic Airway Interventions: Insights from an Indian Tertiary Care Center”. 2026. Monaldi Archives for Chest Disease, April. https://doi.org/10.4081/monaldi.2026.3686.