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Chronic rhinosinusitis with nasal polyps: 64 pheno-endotypes for personalized therapy. Time to change the paradigm
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Published: 19 December 2025
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Dear Editor,
Chronic rhinosinusitis with nasal polyps is still often considered, both in clinical practice and in the literature, as a homogeneous entity...
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Citations
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Gelardi M, Giancaspro R, Duda L, et al. Eosinophil-mast cell pattern of intraepithelial infiltration as a marker of severity in CRSwNP. Sci Rep 2023;13:12101. DOI: https://doi.org/10.1038/s41598-023-39149-8
Gelardi M, Cassano M, Ciprandi G. Clinical relevance of cytological grading in CRSwNP. J Allergy Clin Immunol 2020;146:462-3. DOI: https://doi.org/10.1016/j.jaci.2020.04.049
Gelardi M, Giancaspro R, Quaranta VN, et al. Dupilumab's impact on nasal cytology: real life experience after 1 year. Am J Otolaryngol 2024;45:104275. DOI: https://doi.org/10.1016/j.amjoto.2024.104275
Gelardi M, Netti GS, Giancaspro R, et al. Galectin-10 and cytological grading in CRSwNP. Am J Rhinol Allergy 2022;36:229-37. DOI: https://doi.org/10.1177/19458924211049867
Fokkens WJ, Viskens AS, Backer V, et al. EPOS/EUFOREA update on biologics in CRSwNP. Rhinology 2023;61:194-202.
Dianzani MU. General pathology. First edition. Turin, Italy: UTET; 1974.
How to Cite
“Chronic Rhinosinusitis With Nasal Polyps: 64 Pheno-Endotypes for Personalized Therapy. Time to Change the Paradigm”. 2025. Monaldi Archives for Chest Disease, December. https://doi.org/10.4081/monaldi.2025.3645.
Copyright (c) 2025 The Author(s)
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