Pneumology - Original Articles
June 9, 2025

Asthma-chronic obstructive pulmonary disease misdiagnosis: cause for concern or false alarm?

Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
0
Views
0
Downloads

Authors

Chronic obstructive pulmonary disease (COPD) and asthma are both heterogeneous disorders characterized by overlapping respiratory symptoms. Due to overlapping symptoms and underuse of spirometry, there is often misdiagnosis between these two disorders. A cross-sectional observational study was carried out at the respiratory outpatient department (OPD) of a tertiary care respiratory center in western Maharashtra for 1 year. All patients over the age of 40 who were diagnosed with asthma or COPD and were referred to the respiratory OPD for management or were already under follow-up at the center were included in the study. Questionnaires and spirometry were used to evaluate all patients. A total of 85 patients who met the inclusion criterion without any exclusion requirements were included; 5 patients out of 45 who were initially labelled as having asthma (11.11%) and 29 patients out of 40 who were initially labelled as having COPD (72.5%) were found to have been misdiagnosed according to study protocol. In conclusion, there is a significant prevalence of misdiagnosis amongst obstructive airway disease. The patients with a diagnostic label of COPD are more likely to be misdiagnosed due to a lack of knowledge of diagnostic protocol, underuse and misinterpretation of spirometry, and overreliance on chest radiography. Use of spirometry is dismally low and correlates with other studies from India. The study clearly indicates the urgent requirement of educating doctors, especially primary care clinicians, about the correct diagnostic protocols used in the diagnosis of COPD and bronchial asthma.

Altmetrics

Downloads

Download data is not yet available.

Citations

Global Initiative for Asthma. Global strategy for asthma management and prevention, 2023. Available from: www.ginasthma.org.
Global Initiative for Chronic Obstructive Lung Disease. Global strategy for prevention, diagnosis, and management of COPD: 2024 report. Available from: https://goldcopd.org/2024-gold-report/.
Heffler E, Crimi C, Mancuso S, et al. Misdiagnosis of asthma and COPD and underuse of spirometry in primary care unselected patients. Respir Med 2018;142:48-52.
Vanjare N, Chhowala S, Madas S, et al. Use of spirometry among chest physicians and primary care physicians in India. NPJ Prim Care Respir Med 2016;26:16036.
Salvi SS, Apte KK, Dhar R, et al. Asthma insights and management in India: lessons learned from the Asia Pacific - asthma insights and management (AP-AIM) study. J Assoc Physicians India 2015;63:36-43.
Barnes PJ. Mechanisms in COPD: differences from asthma. Chest 2000;117:10S-4S.
Barthwal MS, Singh S. Early detection of chronic obstructive pulmonary disease in asymptomatic smokers using spirometry. J Assoc Physicians India 2014;62:238-42.
Fagerstrom KO. Can reduced smoking be a way for smokers not interested in quitting to actually quit? Respiration 2005;72:216-20.
Jindal SK, Malik SK. Smoking index – a measure to quantify cumulative smoking exposure. Lung India 1988;VI:195-96.
Tinkelman DG, Price DB, Nordyke RJ, Halbert RJ. Misdiagnosis of COPD and asthma in primary care patients aged 40 years and over. J Asthma 2006;43:75-80.
Gorecka D, Bednarek M, Nowinski A, et al. Diagnosis of airflow limitation combined with smoking cessation advice increases stop-smoking rate. Chest 2003;123:1916-23.
Scanlon PD, Connett JE, Waller LA, et al. Smoking cessation and lung function in mild-to-moderate chronic obstructive pulmonary disease: the Lung Health Study. Am J Respir Crit Care Med 2000;161:381-90.
Bellia V, Battaglia S, Catalano F, et al. Aging and disability affect misdiagnosis of COPD in elderly asthmatics: the SARA study. Chest 2003;123:1066-72.

How to Cite



“Asthma-Chronic Obstructive Pulmonary Disease Misdiagnosis: Cause for Concern or False Alarm?”. 2025. Monaldi Archives for Chest Disease, June. https://doi.org/10.4081/monaldi.2025.3452.