Impact of percutaneous coronary intervention on renal function in patients with coronary heart disease
Accepted: October 14, 2023
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
The relationship between cardiac and renal function is complicated. The impact of percutaneous coronary intervention (PCI) on renal function in patients with coronary artery disease is still unclear. The current study sought to assess renal function change, including the time course of renal function, after elective PCI in patients with improved renal function (IRF) and to identify renal function predictors of major adverse cardiovascular events (MACE). We examined data from 1572 coronary heart disease patients who had coronary angiography (CAG) or PCI in this retrospective cohort study. Patients receiving elective PCI (n=1240) and CAG (n=332) between January 2013 and December 2018 were included. Pre-PCI and procedural variables associated with post-PCI estimated glomerular filtration rate (eGFR), change in renal function after post-PCI follow-up, and post-PCI eGFR association with MACE were investigated. Following the procedure, 88.7% of PCI group patients had unchanged IRF. The treatment of PCI was found to independently correlate with IRF following CAG in an analysis of patients undergoing PCI [odds ratio 4.561 (95% confidence interval: 2.556-8.139); p<0.001]. The area under the receiver operating characteristic curve is 0.763 (model with the treatment of PCI). IRF and stable renal function were both associated with a lower risk of a MACE.
Ethics Approval
The study protocol has been approved by the institutional review board. The committee assessed the planned project as ethically unobjectionable.How to Cite

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.