Can percussive intrapulmonary ventilation improve the efficacy of physiotherapy in children with cystic fibrosis?

Submitted: November 11, 2022
Accepted: March 2, 2023
Published: March 13, 2023
Abstract Views: 993
PDF: 355
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Lung disease in cystic fibrosis (CF) is characterized by reduced mucociliary clearance, airway plugging, recurrent infections, and chronic pulmonary inflammation. Patients who are affected undergo daily respiratory physiotherapy to improve airway clearance. Intrapulmonary percussive ventilation (IPV) is a technique used in clinical practice, but it is not commonly used in CF patients. Evidence for various respiratory pathologies, particularly in children, is still lacking. We present the case of an 11-year-old boy with cystic fibrosis who did not respond to traditional respiratory physiotherapy techniques. We proposed and tested the use of IPV during hospitalization. In this case, the use of IPV in physiotherapy treatment reduced the need for intravenous antibiotics, hospitalization, and improved radiologic features. IPV can be used successfully in CF patients who are resistant to traditional physiotherapy techniques.



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International Physiotherapy Group for Cystic Fibrosis. Physiotherapy for people with cystic fibrosis: from infant to adult. 7th edition 2019. Available from: Accessed in: February 2022.
Lauwers E, Ides K, Van Hoorenbeeck K, Verhulst S. The effect of intrapulmonary percussive ventilation in pediatric patients: a systematic review. Pediatr Pulmonol 2018;53:1463-74.
Reychler G, Debier E, Contal O, Audag N. Intrapulmonary percussive ventilation as an airway clearance technique in subjects with chronic obstructive airway diseases. Respir Care 2018;63:620-31.
Riffard G, Toussaint M. Indications de la ventilation à percussions intrapulmonaires (VPI): revue de la littérature. Rev Mal Respir 2012;29:178-90. [Article in French].
Dingemans J, Eyns H, Willekens J, et al. Intrapulmonary percussive ventilation improves lung function in cystic fibrosis patients chronically colonized with Pseudomonas aeruginosa: a pilot cross-over study. Eur J Clin Microbiol Infect Dis 2018;37:1143-51.

Ethics Approval

This report was approved by the Paediatric Ethics Committee of Meyer Children’s Hospital of Florence (CS_02/2022).

How to Cite

Innocenti, Diletta, Chiara Castellani, Eleonora Masi, Valeria Galici, Letizia Macconi, and Giovanni Taccetti. 2023. “Can Percussive Intrapulmonary Ventilation Improve the Efficacy of Physiotherapy in Children With Cystic Fibrosis?”. Monaldi Archives for Chest Disease 94 (1).