Specific antibody deficiency to pneumococcal polysaccharide in a young adult with recurrent respiratory infections: a case report

Submitted: October 10, 2022
Accepted: November 11, 2022
Published: November 16, 2022
Abstract Views: 983
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Specific antibody deficiency against pneumococcal serotypes was detected in a patient with recurrent episodes of fever. A 21-year-old man presented with a two-month history of recurrent episodes of fever and shaking chills. He was diagnosed with recurrent episodes of pneumonia caused by Streptococcus pneumoniae serotype 19A and treated with amoxicillin. Serotype-specific antibodies were not produced against most of the serotypes, which were consistent with moderate specific antibody deficiency. After pneumococcal 13-valent conjugate vaccination and pneumococcal polysaccharide vaccination, he adequately responded to the infecting serotype with an antibody titer of 1.1 µg/mL. There were eventually no recurrent episodes of fever with pneumonia.

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How to Cite

Ishimaru, Naoto, Yohei Kanzawa, Takahiro Nakajima, Kayoko Okamura, Eiichiro Sando, Isao Ito, Saori Kinami, and Hisashi Ohnishi. 2022. “Specific Antibody Deficiency to Pneumococcal Polysaccharide in a Young Adult With Recurrent Respiratory Infections: A Case Report”. Monaldi Archives for Chest Disease 93 (3). https://doi.org/10.4081/monaldi.2022.2454.