Complete persistent remission of rheumatoid arthritis after COVID-19 infection - A rare case and literature review

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Submitted: January 7, 2022
Accepted: June 6, 2022
Published: June 8, 2022
Abstract Views: 1386
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A 55-year-old man was admitted to a hospital in Northeast India with fever, cough and breathlessness and was diagnosed with severe COVID-19 pneumonia. He was a known case of seropositive, erosive rheumatoid arthritis (RA) and was taking disease-modifying anti-rheumatic drugs (DMARDs). The patient was treated with remdesivir, heparin and a short course of corticosteroids for COVID-19 pneumonia. With the improvement of COVID-19 pneumonia, the patient also noticed a marked improvement in his joint symptoms despite not taking any DMARDs for RA. The temporal relationship between the time of disappearance of all signs and symptoms of RA within a few days after COVID-19 pneumonia and maintenance of RA remission for over one year of follow up to date suggests that COVID-19 likely caused the remission of RA. This case highlights the need for larger studies to understand the COVID-19 effects on RA remission and their potential link if any. However, the evidence of worse outcome with COVID-19 in immunosuppression which is common in RA cannot be overlooked.

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Citations

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How to Cite

Barman, Bhupen, Arvind Nune, Pranav Ish, Pranjal Phukan, Donboklang Lynser, and Hem Raj Sapkota. 2022. “Complete Persistent Remission of Rheumatoid Arthritis After COVID-19 Infection - A Rare Case and Literature Review”. Monaldi Archives for Chest Disease 93 (1). https://doi.org/10.4081/monaldi.2022.2195.