https://doi.org/10.4081/monaldi.2022.2135

Effect of COVID-19 vaccination status on outcome of adult patients admitted at a tertiary care centre in India

Image by <a href="https://pixabay.com/users/geralt-9301/?utm_source=link-attribution&amp;utm_medium=referral&amp;utm_campaign=image&amp;utm_content=6109246">Gerd Altmann</a> from <a href="https://pixabay.com//?utm_source=link-attribution&amp;utm_medium=referral&amp;utm_campaign=image&amp;utm_content=6109246">Pixabay</a>
Vol. 93 No. 1 (2023)
Submitted: October 24, 2021
Accepted: April 13, 2022
Published: April 19, 2022
COVID-19, Mortality, Vaccine
Abstract Views: 1040
PDF: 201
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

Bineet Ahluwalia
Department of Pulmonary and Critical Care Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi , India.
Neeraj Kumar Gupta
Department of Pulmonary and Critical Care Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi , India.
Amitabh Singh
Department of Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Pranav Ish
Department of Pulmonary and Critical Care Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi , India.
Nishanth Dev
Department of Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Santvana Kohli
Department of Anesthesiology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Rohit Kumar
Department of Pulmonary and Critical Care Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi , India.
Fellisha Marwein
Department of Pulmonary and Critical Care Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi , India.
Nitesh Gupta
niteshgupta2107@gmail.com
Department of Pulmonary and Critical Care Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi , India.

COVID-19 vaccination was initially started in India on 16th January 2021 after approval from national authorities. This study was carried out to assess the effect of vaccination status on the severity and clinical outcome among patients infected with COVID-19. The study included all adult COVID-19 patients admitted to our hospital from 1st April to 30th June 2021. A total of 819 patients were enrolled in the study out of which only 183 (22.3%) were vaccinated. The study documented a statistically significant reduction in the severity of illness among the vaccinated (single/double dose) (33% severe COVID-19) against the unvaccinated (43% severe COVID-19) groups; along with a reduction in mortality. On univariate and multivariate analysis, age, severity of illness and lack of COVID-19 vaccination status were associated with a statistically significant increased mortality. To conclude, this study demonstrates the role of vaccination in decreasing the severity and mortality of COVID-19 infection.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

Citations

Crossref
Scopus
Google Scholar
Europe PMC
Srivastava RK, Ish P, Covid-Vaccination Group. The initial experience of COVID-19 vaccination from a tertiary care centre of India. Monaldi Arch Chest Dis 2021;91:1816. DOI: https://doi.org/10.4081/monaldi.2021.1816
Kunal S, Aditi, Gupta K, Ish P. COVID-19 variants in India: Potential role in second wave and impact on vaccination. Heart Lung 2021;50:784-7. DOI: https://doi.org/10.1016/j.hrtlng.2021.05.008
Government of India, Ministry of Health and Family Welfare. Clinical management protocol: COVID-19. Accessed on 5 July 2021. Available from: https://www.mohfw.gov.in/pdf/ClinicalManagementProtocolforCOVID19.pdf
Ish P, Sakthivel P, Gupta N, et al. ABC triage and protect phase strategy in COVID-19 management: lessons from the past. Postgrad Med J 2022;98:e127-28. DOI: https://doi.org/10.1136/postgradmedj-2020-139114
Jain VK, Iyengar KP, Ish P. Elucidating causes of COVID-19 infection and related deaths after vaccination. Diabetes Metab Syndr 2021;15:102212. DOI: https://doi.org/10.1016/j.dsx.2021.102212
Moghadas SM, Vilches TN, Zhang K, et al. The impact of vaccination on COVID-19 outbreaks in the United States. Clin Infect Dis 2021;73:2257-64. DOI: https://doi.org/10.1093/cid/ciab079
Haghpanah F, Lin G, Levin SA, Klein E. Analysis of the potential impact of durability, timing, and transmission blocking of COVID-19 vaccine on morbidity and mortality. EClinicalMedicine 2021;35:100863. DOI: https://doi.org/10.1016/j.eclinm.2021.100863
Iyengar KP, Singh B, Vaishya R, et al. Should COVID-19 vaccination be made mandatory? Lung India 2021;38:379-81. DOI: https://doi.org/10.4103/lungindia.lungindia_181_21

How to Cite

Ahluwalia, Bineet, Neeraj Kumar Gupta, Amitabh Singh, Pranav Ish, Nishanth Dev, Santvana Kohli, Rohit Kumar, Fellisha Marwein, and Nitesh Gupta. 2022. “Effect of COVID-19 Vaccination Status on Outcome of Adult Patients Admitted at a Tertiary Care Centre in India”. Monaldi Archives for Chest Disease 93 (1). https://doi.org/10.4081/monaldi.2022.2135.
Copyright (c) 2022 The Author(s) Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.