Aortic thrombosis: the forgotten source of ischemic stroke. A case report and systematic review of the literature

Ischemic stroke in the pontine anterior and medianparamedian left regions at the brain MRI.
Published: December 3, 2021
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Ischemic stroke represents one of the most important health problems in industrialized countries, both for epidemiological and socio-economic impact. The presence of thrombi in the aorta is rare and its treatment has not been uniquely defined. Here we report the case of an 82-years-old man with aortic thrombosis and acute ischemic stroke.



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Majersik JJ, Woo D. The enormous financial impact of stroke disability. Neurology 2020;94:377-8. DOI:
Erbel R, Aboyans V, Boileau C, et al. 2014 ESC Guidelines on the diagnosis and treatment of aortic diseases: Document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult. The Task Force for the Diagnosis and Treatment of Aortic Diseases of the European. Eur Heart J 2014;35:2873-926. DOI:
Sachdev S, Bardia N, Nguyen L, Omar B. Bioprosthetic valve thrombosis. Cardiol Res 2018;9:335-42. DOI:
Pradegan N, Basso C, Della Barbera M, et al. Cardiac arrest due to acute massive aortic root thrombosis after pericardial bioprosthetic aortic valve replacement. Cardiovasc Pathol 2019;41:8-10. DOI:
Yamase Y, Kuwabara F, Watanabe K, et al. A case of floating thrombus in the ascending aorta that caused recurrent peripheral arterial embolic events. J Cardiol Cases 2015;12:57-60. DOI:
Bowdish ME, Weaver FA, Liebman HA, et al. Anticoagulation is an effective treatment for aortic mural thrombi. J Vasc Surg 2002;36:713-9. DOI:
Reber PU, Patel AG, Stauffer E, et al. Mural aortic thrombi: An important cause of peripheral embolization. J Vasc Surg 1999;30:1084-9. DOI:
Barry N, Tsui J, Dick J, et al. Aortic tumor presenting as acute lower limb ischemia. Circulation 2011;123:1785-7. DOI:
Stoevesandt D, Klempt C, Scheubel R, et al. Embolic events caused by aortic thrombi: an underestimated entity? J Thromb Thrombolysis 2013;35:223-7. DOI:
Yang P, Li Y, Huang Y, et al. A giant floating thrombus in the ascending aorta: a case report. BMC Surg 2020;20:321. DOI:
Dhillon P, Murdoch D, Jayasinghe R, Niranjan S. A case of mobile aortic arch thrombus with systemic embolisation, a management dilemma. Heart Lung Circ 2014;23:e88-91. DOI:
Houmsse M, McDavid A, Kilic A. Large de novo ascending aortic thrombus successfully treated with anticoagulants. J Cardiovasc Thorac Res 2018;10:113-4. DOI:
Scott DJ, White JM, Arthurs ZM. Endovascular management of a mobile thoracic aortic thrombus following recurrent distal thromboembolism: a case report and literature review. Vasc Endovascular Surg 2014;48:246-50. DOI:
de Maat GE, Vigano G, Mariani MA, Natour E. Catching a floating thrombus; a case report on the treatment of a large thrombus in the ascending aorta. J Cardiothorac Surg 2017;12:34. DOI:
Campanile A, Sardone M, Pasquino S, et al. Surgical management of a free-floating thrombus in the ascending aorta. Asian Cardiovasc Thorac Ann 2019;27:221-3. DOI:
Wang B, Ma D, Cao D, Man X. Huge thrombus in the ascending aorta: a case report and literature review. J Cardiothorac Surg 2019;14:157. DOI:
Tunick PA, Kronzon I. Atheromas of the thoracic aorta: clinical and therapeutic update. J Am Coll Cardiol 2000;35:545-54. DOI:
Laperche T, Laurian C, Roudaut R, Steg PG. Mobile thromboses of the aortic arch without aortic debris. A transesophageal echocardiographic finding associated with unexplained arterial embolism. The Filiale Echocardiographie de la Société Française de Cardiologie. Circulation 1997;96:288-94. DOI:
Reyes Valdivia A, Duque Santos A, Garnica Ureña M, et al. anticoagulation alone for aortic segment treatment in symptomatic primary aortic mural thrombus patients. Ann Vasc Surg 2017;43:121-6. DOI:

How to Cite

Basile, Christian, Costantino Mancusi, Paola Gargiulo, Pasquale Perrone Filardi, Cinzia Perrino, Grazia Canciello, Maria Angela Losi, and Giovanni Esposito. 2021. “Aortic Thrombosis: The Forgotten Source of Ischemic Stroke. A Case Report and Systematic Review of the Literature”. Monaldi Archives for Chest Disease 92 (3).