Prevalence of aspergillus skin hypersensitivity in allergic rhinitis

Submitted: May 28, 2020
Accepted: March 2, 2021
Published: March 9, 2021
Abstract Views: 1589
PDF: 510
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.


Allergic rhinitis (AR) is a chronic allergen specific, IgE-mediated hypersensitivity disorder which significantly impairs the quality of life in affected patients. Many aeroallergens and molds are responsible for AR. This study was  conducted to find prevalence of Aspergillus fumigatus skin hypersensitivity in patients of AR by skin prick test (SPT).  150 clinically diagnosed AR patients visiting our OPD were enrolled. Skin hypersensitivity for Aspergillus f. was done by SPT in all the enrolled patients. Chi square test and Student’s t-test were applied for statistical analysis. Out of 150 patients, 60 (40%) were positive for Aspergillus fumigatus SPT. Majority of the positive patients had persistent AR and among those 39/60 (65%) had moderate to severe persistent AR and 12/60 (20%) had mild persistent AR.  Our study concluded that there is high (40%) prevalence of Aspergillus f. skin hypersensitivity among AR patients. The hypersensitivity to Aspergillus f. was found more in severe AR patients and it was statistically significant.



PlumX Metrics


Download data is not yet available.


Bousquet J, Khaltaev N, Cruz AA, et al. Allergic rhinitis andits impact on asthma (ARIA) 2008 update (in collaboration
with the World Health Organization, GA2LEN and AllerGen). Allergy 2008;63:8-160.
Brozek JL, Bousquet J, Agache I, et al. Allergic rhinitis and its impact on asthma (ARIA) guidelines—2016 revision. J Allergy Clin Immunol 2017;140:950-8. DOI:
Aggarwal D, Abhilash S, Kapur S, Gupta D. Study of causal aeroallergens in allergic rhinitis. Int J Otorhinolaryngol Head Neck Surg 2019;5:916-21. DOI:
Simon-nobbe B, Denk U, Poll V, et al. The spectrum of fungal allergy. Int Arch Allergy Immunol 2008;145:58-86. DOI:
Bignardi D, Comite P, Mori I, et al. Allergen-specific IgE: comparison between skin prick test and serum assay in real life. Allergol Select 2019;3:9-14. DOI:
Ibekwe PU, Ibekwe TS. Skin prick test analysis in allergic rhinitis patients: a preliminary study in Abuja , Nigeria. J Allergy 2016;2016:1-5. DOI:
Todo-Bom A, Braido F, Molinengo G, et al. The Portuguese version of rhinitis and asthma patient’s perspective (RAPP): validation and assessment. Pulmonology 2020;26:73-7. DOI:
Sharma RK, Mathur Y, Chhabra G, et al. A study of skin sensitivity to various allergens by skin prick test in patients of bronchial asthma and allergic rhinitis. Indian J Allergy Asthma Immunol 2018;32:47-53. DOI:
Chogtu B, Magaji N, Magazine R, Acharya PR. Pattern of allergen sensitivity among patients with bronchial asthma and/or allergic rhinosinusitis in a tertiary care centre of southern India. J Clin Diagn Res 2017;11:OC01-4. DOI:
Hakkim FA, Rajesh V, Giridhar, et al. A study on profile of allergens and the severity of FEV1 in allergy patients in a tertiary care centre in Mangalore, India. Int J Med Res Health Sci 2018;7:135-40.
Dhanya EK, Rajesh V, Augustine J, et al. Sensitivity pattern to common inhalant allergens in subjects with allergic rhinitis in Kerala. Eur J Pharm Med Res 2019;6:584-7.
Sinha B, Vibha, Singla R, Chowdhury R. Allergic rhinitis: A neglected disease - a community based assessment among adults in Delhi. J Postgrad Med 2015;61:169-75. DOI:
Dave L, Srivastava N. A study of sensitisation pattern to various aero-allergens by skin prick test in patients of united airway disease (UAD) in Bhopal, Madhya Pradesh, India. Res J Pharm Biol Chem Sci 2014;5:1397-403.

How to Cite

Bansal, Monika, Komaldeep Kaur, Aditi Gupta, Deepak Goyal, Nidhi Girdhar, Vishal Chopra, Sanjeev Bhagat, and Akhil D. Goel. 2021. “Prevalence of Aspergillus Skin Hypersensitivity in Allergic Rhinitis”. Monaldi Archives for Chest Disease 91 (3).