Probe-based confocal laser endomicroscopy in diagnosis of desquamative interstitial pneumonia in nonsmoker

Submitted: February 22, 2019
Accepted: July 5, 2019
Published: September 10, 2019
Abstract Views: 1086
PDF: 625
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Desquamative interstitial pneumonia is a rare disease that is predominantly associated with smoking. Surgical biopsy is usually recommended for the diagnosis of this disorder. Probe-based confocal laser endomicroscopy (pCLE) is a new method of minimally invasive in vivo microscopic image of airways and alveoli. We use this method for desquamative interstitial pneumonia in nonsmoker. The pCLE image shows thickened intra-alveolar septae and clusters of autofluorescent cells within the alveoli, which is unusual for non-smoking patients. We think this pattern can be used for differential diagnosis of desquamative interstitial pneumonia in nonsmokers.



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How to Cite

Mamenko, Igor S., Igor V. Vasilev, Irina A. Tabanakova, Sultan M. Gasanmagomedov, Vera V. Sysoeva, Alexey D. Ushkov, Tatiana A. Novickaya, and Piotr K. Yablonskii. 2019. “Probe-Based Confocal Laser Endomicroscopy in Diagnosis of Desquamative Interstitial Pneumonia in Nonsmoker”. Monaldi Archives for Chest Disease 89 (3).