Non-small cell lung cancer presenting as "psoas muscle syndrome": a case report

Submitted: November 28, 2018
Accepted: February 5, 2019
Published: April 5, 2019
Abstract Views: 1581
PDF: 997
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Lung cancer is the leading cause of cancer-related death worldwide and majority of patients are diagnosed in advanced/metastatic disease stage. Sites of distant metastases mainly include contralateral lung, lymph nodes, brain, bones, adrenal glands and liver; skeletal muscles metastases (SMMs) are less common. Psoas muscle and diaphragm metastases are mainly found during autopsy, as their involvement commonly is asymptomatic. We report a case of a 60-year-old female, suffering from non-small cell lung cancer (NSCLC), with refractory lower back pain, as expression of malignant psoas syndrome (MPS). MPS is a rare and difficult-to-treat cancer-pain syndrome, unresponsive to majority of analgesic therapy, related to psoas muscle metastasis; it is usually caused by different tumors such as uterus, ovary, bladder, prostate, colon-rectum, lymphoma, melanoma and sarcoma and represents an uncommon finding in NSCLC patients. 

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Mollica, Mariano, Rosalba Maffucci, Sabrina Lavoretano, Gaetano Rea, Francesco Saverio Cerqua, Luigi Aronne, Andrea Bianco, and Fabio Perrotta. 2019. “Non-Small Cell Lung Cancer Presenting As ‘psoas Muscle syndrome’: A Case Report”. Monaldi Archives for Chest Disease 89 (1). https://doi.org/10.4081/monaldi.2019.1012.