https://doi.org/10.4081/monaldi.2013.19

Epicardial adipose tissue and insulin resistance in patients with coronary artery disease with or without left ventricular dysfunction

Vol. 80 No. 4 (2013): Cardiac Series
Published: December 30, 2013
Epicardial fat, insulin resistance, coronary artery disease, adipokine, left ventricular dysfunction.
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Authors

Samuele Baldasseroni
pesine@libero.it
Department of Clinical and Experimental Medicine, Geriatric Cardiology and Medicine Unit, University of Florence; Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.
Alessandra Pratesi
Department of Clinical and Experimental Medicine, Geriatric Cardiology and Medicine Unit, University of Florence; Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.
Francesco Orso
Department of Clinical and Experimental Medicine, Geriatric Cardiology and Medicine Unit, University of Florence; Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.
Claudia Di Serio
Department of Clinical and Experimental Medicine, Geriatric Cardiology and Medicine Unit, University of Florence; Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.
Alice Foschini
Department of Clinical and Experimental Medicine, Geriatric Cardiology and Medicine Unit, University of Florence; Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.
Andrea Giosafat Marella
Department of Clinical and Experimental Medicine, Geriatric Cardiology and Medicine Unit, University of Florence; Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.
Nadia Bartoli
Department of Clinical and Experimental Medicine, Geriatric Cardiology and Medicine Unit, University of Florence; Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.
Mauro Di Bari
Department of Clinical and Experimental Medicine, Geriatric Cardiology and Medicine Unit, University of Florence; Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.
Stefano Fumagalli
Department of Clinical and Experimental Medicine, Geriatric Cardiology and Medicine Unit, University of Florence; Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.
Niccolò Marchionni
Department of Clinical and Experimental Medicine, Geriatric Cardiology and Medicine Unit, University of Florence; Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.
Francesca Tarantini
Department of Clinical and Experimental Medicine, Geriatric Cardiology and Medicine Unit, University of Florence; Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.
Background. Epicardial adipose tissue (EAT) is a visceral fat that fulfills two important functions: lipid-storage and secretion of adipokines with pro-inflammatory and pro-atherogenic properties. It has been suggested that EAT may affect the pathogenesis of atherosclerosis and the clinical course of coronary artery disease (CAD). In patients with obesity, diabetes and metabolic syndrome, the epicardial adipose tissue is enlarged. Little is known about the role of EAT in left ventricular dysfunction. Aim of this study was to evaluate the ability of insulin resistance to predict EAT thickness in patients with significant CAD and systolic dysfunction. Methods. We enrolled 114 subjects diagnosed with CAD by angiography. The majority underwent revascularization after an acute coronary syndrome. Patients were considered affected by significant left ventricular dysfunction when EF was

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How to Cite

Baldasseroni, Samuele, Alessandra Pratesi, Francesco Orso, Claudia Di Serio, Alice Foschini, Andrea Giosafat Marella, Nadia Bartoli, Mauro Di Bari, Stefano Fumagalli, Niccolò Marchionni, and Francesca Tarantini. 2013. “Epicardial Adipose Tissue and Insulin Resistance in Patients With Coronary Artery Disease With or Without Left Ventricular Dysfunction”. Monaldi Archives for Chest Disease 80 (4). https://doi.org/10.4081/monaldi.2013.19.

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