Distinct phenotypes in COVID-19 may require distinct pulmonary rehabilitation strategies


The novel coronavirus (SARS-CoV-2) has distinct clinical manifestations that can vary from an asymptomatic condition to severe acute respiratory failure. Phenotypes are attributable to different pathophysiological mechanisms and require different treatment strategies. The assessment and identification of different phenotypes can guide therapy configurations such as oxygen therapy, non-invasive ventilation, airway management, and tracheal intubation. Further studies are essential to provide information on the influence of phenotypes in the decision of rehabilitation strategies. The sequelae left in the respiratory system of COVID-19 survivors and its limitations will be a challenge for rehabilitation services worldwide. Lung injuries are directly related to the phenotypes presented, and depending on the degree of these injuries, rehabilitation strategies can be targeted. We believe that differentiating patients, according to their respective phenotypes, can improve decision-making in treatment and individualized rehabilitation.



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Author Biography

Maria do Socorro Brasileiro-Santos, Department of Physiotherapy and Postgraduate Program in Physiotherapy, Federal University of Paraiba, João Pessoa

Department of Physical Education, Federal University of Paraiba; Associate Graduate Program in Physical Education, UPE-UFPB

COVID-19 - Collection of articles on the Coronavirus outbreak
COVID-19, pneumonia, phenotypes, physical and rehabilitation medicine
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How to Cite
de França, E. E. T., Junior, U. E., Schwingel, P. A., Carvalho, C. R., & Brasileiro-Santos, M. do S. (2020). Distinct phenotypes in COVID-19 may require distinct pulmonary rehabilitation strategies. Monaldi Archives for Chest Disease, 90(4). https://doi.org/10.4081/monaldi.2020.1523