Case Reports
June 30, 2005
Vol. 63 No. 2 (2005): Pulmonary series
https://doi.org/10.4081/monaldi.2005.649

Mediastinal Images Resembling Thymus Following 131-I Treatment for Thyroid Cancer

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Thyroid cancer, thymic hyperplasia, 131-I therapy, whole body scan
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Authors

L. Montella
lilianamontella@libero.it
Medical Oncology Department, “S.Giovanni di Dio” Hospital, Frattaminore, Naples, Italy.
M. Caraglia
National Cancer Institute of Naples, “Fondazione G. Pascale”, Naples, Italy.
A. Abbruzzese
Dept. Biochemistry and Biophysics, Second University of Naples, Naples, Italy.
A. Soricelli
Diagnostic Imaging and Radiotherapy Department - National Research Center, University “Federico II”, Naples, Italy.
M. Caputi
Department of Cardiothoracic and Respiratory Sciences, 2nd University of Naples, Italy.
G. Squame
Diagnostic Imaging and Radiotherapy Department - National Research Center, University “Federico II”, Naples, .
M. Salvatore
Diagnostic Imaging and Radiotherapy Department - National Research Center, University “Federico II”, Naples, Italy.
S. Del Prete
Medical Oncology Department, “S.Giovanni di Dio” Hospital, Frattaminore, Naples, Italy.
G. Palmieri
Molecular and Clinical Endocrinology and Oncology Department, University “Federico II”, Naples, Italy.
The follow-up of Differentiated Thyroid Cancer conventionally includes serum thyroglobulin and periodic Whole Body Scans. The uptake of 131-I in normal and pathological tissues different from metastatic thyroid cancer sites is a cause of false-positive scans. Among them, mediastinal uptake caused by thymic hyperplasia can be observed. The aim of the present study was to review a series of 573 patients with differentiated thyroid cancer treated with 131-I after surgery between 1992 and 2003 looking above all for those with mediastinal images resembling thymus. This evaluation is presented together with some hypotheses on the relationships between thymus and thyroid. Moreover, some considerations are made on the differential diagnosis between thymus and mediastinal tumour thyroid residues.

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“Mediastinal Images Resembling Thymus Following 131-I Treatment for Thyroid Cancer”. 2005. Monaldi Archives for Chest Disease 63 (2). https://doi.org/10.4081/monaldi.2005.649.