Pneumology - Reviews
Early Access
From benign airway lesions to bioengineered solutions: 3D bioprinting in tracheobronchopathia osteochondroplastica
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Published: 21 July 2026
0
Views
0
Downloads
Authors
Tracheobronchopathia osteochondroplastica is a rare benign lesion of the airways often managed conservatively. However, advanced obstruction requires reconstruction. This brief commentary explores the emerging role of 3D bioprinting as a curative solution, analyzing recent findings regarding mesenchymal stem cell-laden grafts and identifying vascularization as the critical hurdle preventing clinical translation.
Downloads
Download data is not yet available.
Citations
Gaddam M, Tangutoori S, Gullapalli D, et al. A bumpy ride through a turbulent airway: but not always. SAGE Open Med Case Rep 2025;13:23247096251357757.
Liang Y, Wei S, Zhang A. Bioengineered tracheal graft with enhanced vascularization and mechanical stability for functional airway reconstruction. Regen Ther 2025;29:364-80.
McMillan A, Hoffman MR, Xu Y, et al. 3D bio-printed ferret mesenchymal stem cell-laden cartilage grafts for laryngotracheal reconstruction in a ferret surgical model. Biomater Sci 2025;13:1304-22.
Kim IG, Park SA, Lee SH, et al. Transplantation of a 3D-printed tracheal graft combined with iPS cell-derived MSCs and chondrocytes. Sci Rep 2020;10:4326.
How to Cite
“From Benign Airway Lesions to Bioengineered Solutions: 3D Bioprinting in Tracheobronchopathia Osteochondroplastica”. 2026. Monaldi Archives for Chest Disease, July. https://doi.org/10.4081/monaldi.2026.3846.
Copyright (c) 2026 The Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.