Pneumology - Case Reports
Vol. 90 No. 3 (2020)
https://doi.org/10.4081/monaldi.2020.1435

ROS1 positive non-small cell lung cancer with pulmonary embolism in a 22-year woman

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Received: 6 June 2020
Published: 7 August 2020
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ROS1, NSCLC, pulmonary embolism

Authors

Ananda Datta
https://orcid.org/0000-0003-4419-9640
Department of Pulmonary Medicine and Critical Care, All India Institute of Medical Sciences, Bhubaneswar, India.
Satya Padmaja Mantha
https://orcid.org/0000-0001-9544-6539
Department of Pulmonary Medicine and Critical Care, All India Institute of Medical Sciences, Bhubaneswar, India.
Suvradeep Mitra
https://orcid.org/0000-0002-5520-8306
Department of Pathology, All India Institute of Medical Sciences, Bhubaneswar, India.
Prasanta Raghab Mohapatra
prmohapatra@hotmail.com
https://orcid.org/0000-0002-6625-2417
Department of Pulmonary Medicine and Critical Care, All India Institute of Medical Sciences, Bhubaneswar, India.
M Srikanth Goud
https://orcid.org/0000-0001-8480-1259
Department of Pulmonary Medicine and Critical Care, All India Institute of Medical Sciences, Bhubaneswar, India.
Manoj Kumar Panigrahi
https://orcid.org/0000-0002-2743-1068
Department of Pulmonary Medicine and Critical Care, All India Institute of Medical Sciences, Bhubaneswar, India.

ROS1-rearrangement occurs in 1-2% of non-small cell lung cancer (NSCLC). This mutation is predominantly seen in relatively young, non-smoker, female with adenocarcinoma. Association of pulmonary embolism with ROS1-rearranged NSCLC has been suggested. We report a case of a 22-year-old woman with ROS1-positive NSCLC and pulmonary embolism. This case possibly represents the youngest patient in the literature.

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“ROS1 Positive Non-Small Cell Lung Cancer With Pulmonary Embolism in a 22-Year Woman”. 2020. Monaldi Archives for Chest Disease 90 (3). https://doi.org/10.4081/monaldi.2020.1435.

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