Adipokines and coronary artery disease

Submitted: December 1, 2015
Accepted: December 1, 2015
Published: December 1, 2015
Abstract Views: 1414
PDF: 881
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Adipose tissue, besides being an important energetic storage, is also a source of cytokines and hormones which act in a paracrine, autocrine and especially endocrine manner, influencing the cardiometabolic axis. Adipokines are a group of mediators with pleiotropic function, that are involved in many physiological processes, so that a disregulation in their secretion can lead to multiple pathological conditions. In this review our aim was to clarify the role of adipokines in the pathogenesis of atherosclerosis, especially in coronary artery disease, and based on current scientific evidence, to analyze the therapeutic and behavioral strategies that are so far available.

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Strisciuglio, Teresa, Gennaro Galasso, Dario Leosco, Roberta De Rosa, Giuseppe Di Gioia, Valentina Parisi, Stefania De Luca, Tullio Niglio, Chiara De Biase, Rossella Luciano, Giuseppe Rengo, Bruno Trimarco, and Federico Piscione. 2015. “Adipokines and Coronary Artery Disease”. Monaldi Archives for Chest Disease 78 (3). https://doi.org/10.4081/monaldi.2012.117.