High flow nasal cannula in acute hypercapnic exacerbation of chronic obstructive pulmonary disease: an emerging utility

Submitted: August 24, 2019
Accepted: December 15, 2019
Published: January 21, 2020
Abstract Views: 1946
PDF: 1290
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Authors

High flow nasal cannula (HFNC) provides warmed and humidified air with flow rates up to 60 liters/min with relatively fixed oxygen content (FiO2). It has been extensively evaluated for hypoxemic respiratory failure and has been used in mild acute respiratory distress syndrome, pre-intubation, bronchoscopy and pediatric obstructive sleep apnea. Recent data has suggested a role in stable hypercapnic chronic obstructive pulmonary disease (COPD) and even in acute exacerbations, though, the use has not been advocated by any guidelines yet. We present a case of acute hypercapnic exacerbation of COPD, intolerant to non-invasive ventilation, showing response and improvement on use of HFNC. This case highlights this potential mechanisms and prospects for the same.

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Mittal, Anshul, Megha Varshney, Vidushi Rathi, and Pranav Ish. 2020. “High Flow Nasal Cannula in Acute Hypercapnic Exacerbation of Chronic Obstructive Pulmonary Disease: An Emerging Utility”. Monaldi Archives for Chest Disease 90 (1). https://doi.org/10.4081/monaldi.2020.1158.