Pneumology - Case Reports
September 10, 2019

Probe-based confocal laser endomicroscopy in diagnosis of desquamative interstitial pneumonia in nonsmoker

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Desquamative interstitial pneumonia is a rare disease that is predominantly associated with smoking. Surgical biopsy is usually recommended for the diagnosis of this disorder. Probe-based confocal laser endomicroscopy (pCLE) is a new method of minimally invasive in vivo microscopic image of airways and alveoli. We use this method for desquamative interstitial pneumonia in nonsmoker. The pCLE image shows thickened intra-alveolar septae and clusters of autofluorescent cells within the alveoli, which is unusual for non-smoking patients. We think this pattern can be used for differential diagnosis of desquamative interstitial pneumonia in nonsmokers.

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“Probe-Based Confocal Laser Endomicroscopy in Diagnosis of Desquamative Interstitial Pneumonia in Nonsmoker”. 2019. Monaldi Archives for Chest Disease 89 (3). https://doi.org/10.4081/monaldi.2019.1052.