TB Corner
Vol. 61 No. 2 (2004): Pulmonary series
https://doi.org/10.4081/monaldi.2004.712

Difficult diagnosis of Infliximab-related miliary tuberculosis

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Received: 29 February 2016
Published: 30 June 2004
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TNF-α, Infliximab, miliary tuberculosis

Authors

S. Contini
Cattedra di Malattie Respiratorie e Scuola di Specializzazione in Malattie Respiratorie, Università Tor Vergata, Roma, Italy.
G. Raimondi
Divisione Clinicizzata di Malattie Respiratorie INMI L. Spallanzani-IRCCS, Roma, Italy.
P. Graziano
U.O. di Anatomia ed Istologia Patologica, Ospedale C. Forlanini, A.O. San Camillo-Forlanini, Roma, Italy.
C. Saltini
Cattedra di Malattie Respiratorie e Scuola di Specializzazione in Malattie Respiratorie, Università Tor Vergata, Roma, Italy.
M. Bocchino
mlbocchino@tiscali.it
Divisione Clinicizzata di Malattie Respiratorie INMI L. Spallanzani-IRCCS, Roma, Italy.
The use of Infliximab in the treatment of patients with rheumatoid diseases unresponsive to conventional therapies has been reported to be complicated by opportunistic infections. We report the case of a 56-yr old female rheumatoid arthritis patient complaining of fever and respiratory symptoms 9 months after commencing Infliximab, who received no ethiologic diagnosis for the six months before admission. Tuberculosis was suspected upon chest radiographic pictures and empirical treatment for miliary tuberculosis instated in the wake of microbiological confirmation. The case typifies the difficulties of diagnosing miliary tuberculosis in the immunocompromised as well as in the immunocompetent patient.

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“Difficult Diagnosis of Infliximab-Related Miliary Tuberculosis”. 2004. Monaldi Archives for Chest Disease 61 (2). https://doi.org/10.4081/monaldi.2004.712.

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