Clinical features, management and in-hospital outcome of ST elevation myocardial infarction (STEMI) in young adults under 40 years of age

  • Seyed Kianoosh Hosseini | skhoseini@yahoo.com Department of Cardiology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of.
  • Abbas Soleimani Department of Cardiology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of.
  • Abbas Ali Karimi Department of Cardiac Surgery, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of.
  • Saeed Sadeghian Department of Cardiology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of.
  • Sirous Darabian Department of Cardiology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of.
  • Seyed Hesameddin Abbasi Department of Research, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of.
  • Seyed Hossein Ahmadi Department of Cardiac Surgery, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of.
  • Arezou Zoroufian Department of Cardiology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of.
  • Mehran Mahmoodian Department of Research, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of.
  • Ali Abbasi Department of Epidemiology, University Medical Center Groningen, Groningen, Netherlands.

Abstract

Objectives: This study was designed to evaluate the demographic and clinical findings and in-hospital management and outcome in patients with an acute ST-segment elevation myocardial infarction (STEMI). Material and methods: By review of the Cardiovascular Tehran Heart Center Registry (CVDTHCR), 2028 patients were found to have the acute STEMI. We compared the patients’ characteristics in 109 (5.4%) subjects ≤40 and 1919 subjects > 40 years old. Results: The young patients had less diabetes, hypertension, dyslipidemia and history of MI or prior revascularization, and were more likely to be male (92.7% vs. 74%), smoker (58.7% vs. 31.7%) and have family history of CVD (50.5% vs. 23.4%). The young patients had higher prevalence of angiographically normal coronary artery (13.7% vs. 0.9%; p<0.001). The young patients were more likely to undergo percutaneous coronary intervention (38.5% vs. 18.6%), whereas coronary artery bypass grafting was more common in the old ones (p<0.001). In-hospital death was markedly different among young and old patients (0.9% and 6.1%, respectively; p<0.01). Conclusion: In STEMI population, the risk profile, clinical findings and severity of coronary disease of the young differ substantially from the elderly counterparts. Young patients with STEMI have a favorable outcome compared with that in older patients.

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Published
2016-01-20
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Original Articles
Keywords:
ST-segment elevation, myocardial infarction, risk factors, young, coronary artery disease
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How to Cite
Kianoosh Hosseini, S., Soleimani, A., Ali Karimi, A., Sadeghian, S., Darabian, S., Hesameddin Abbasi, S., Hossein Ahmadi, S., Zoroufian, A., Mahmoodian, M., & Abbasi, A. (2016). Clinical features, management and in-hospital outcome of ST elevation myocardial infarction (STEMI) in young adults under 40 years of age. Monaldi Archives for Chest Disease, 72(2). https://doi.org/10.4081/monaldi.2009.331