An uncommon clinical condition: chronic thrombosis of the inferior vena cava. A case report and review of literature

https://doi.org/10.4081/monaldi.2010.278

Authors

  • Francesca Donati | francedonati@hotmail.com Scuola di Specializzazione in Malattie dell’Apparato Cardiovascolare, Cardiothoracic and Vascular Department, University of Pisa, Pisa, Italy.
  • Leonardo Misuraca Scuola di Specializzazione in Malattie dell’Apparato Cardiovascolare, Cardiothoracic and Vascular Department, University of Pisa, Pisa, Italy.
  • Chrysanthos Grigoratos Angiology Division, Cardiothoracic and Vascular Department, Azienda Ospedaliero-Universitaria Pisana, University of Pisa, Pisa, Italy.
  • Caterina Violo Angiology Division, Cardiothoracic and Vascular Department, Azienda Ospedaliero-Universitaria Pisana, University of Pisa, Pisa, Italy.
  • Stefano Vannucci Radiology Department, Azienda Ospedaliero-Universitaria Pisana, University of Pisa, Pisa, Italy.
  • Alberto Balbarini Angiology Division, Cardiothoracic and Vascular Department, Azienda Ospedaliero-Universitaria Pisana, University of Pisa, Pisa, Italy.

Abstract

The lifetime incidence of deep vein thrombosis (DVT) is approximately 0.1% in general population and even more uncommon in subjects below 40 years of age. Thrombosis of the inferior vena cava (IVC) is an exceptionally rare clinical condition, with etiological factors similar to lower limb DVT. We present a case of post-traumatic chronic obstruction of the IVC in 41 years-old man, caused by a prolonged squatted position, while he was working as a bricklayer. We visited the patient fifteen years after the onset of the first clinical setting showing a severe post thrombotic syndrome, as a consequence of the already diagnosticated thrombosis, involving predominantly the right inferior leg. Thrombophilia screening tests showed patient to be a heterozygous carrier of methylenetetrahydrofolate reductase (MTHFR) gene mutation. Computed tomography (CT) scan confirmed the thrombotic obstruction of the infrahepatic IVC, both common iliac veins, right external and internal iliac veins, with multiple collateral pathways. Because of thrombosis extension, inherited prothrombotic condition and the young age of the patient, we decided to continue life-long oral anticoagulant therapy.

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Published
2015-12-23
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Issue
Section
Case Reports
Keywords:
deep vein thrombosis, inferior vena cava thrombosis, inherited thrombophilia, oral anticoagulant therapy
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How to Cite
Donati, Francesca, Leonardo Misuraca, Chrysanthos Grigoratos, Caterina Violo, Stefano Vannucci, and Alberto Balbarini. 2015. “An Uncommon Clinical Condition: Chronic Thrombosis of the Inferior Vena Cava. A Case Report and Review of Literature”. Monaldi Archives for Chest Disease 74 (1). https://doi.org/10.4081/monaldi.2010.278.

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