Platypnea orthodeoxia syndrome in a patient with patent foramen ovale and normal atrial pressure. Case report and presentation of underlying pathophysiological mechanisms

https://doi.org/10.4081/monaldi.2021.1878

Authors

  • Fotios Sampsonas | fsampsonas@gmail.com Respiratory Department, School of Medicine, Patras University Hospital, Greece. https://orcid.org/0000-0002-7796-2959
  • Matthaios Katsaras Respiratory Department, School of Medicine, Patras University Hospital, Greece.
  • Ourania Papaioannou Respiratory Department, School of Medicine, Patras University Hospital, Greece. https://orcid.org/0000-0003-3889-679X
  • Theodoros Karampitsakos Respiratory Department, School of Medicine, Patras University Hospital, Greece.
  • Lampros Lakkas 2nd Department of Cardiology, School of Medicine, University of Ioannina, Greece. https://orcid.org/0000-0001-9401-3125
  • Lampros K. Michalis 2nd Department of Cardiology, School of Medicine, University of Ioannina, Greece.
  • Argyrios Tzouvelekis Respiratory Department, School of Medicine, Patras University Hospital, Greece.

Abstract

Platypnea-orthodeoxia Syndrome is characterized by clinically significant postural hypoxia. The full spectrum of the syndrome includes intracardial and extracardial abnormalities with R->L shunt. Various concurrent underlying physiological abnormalities are usually encountered that require thorough clinical and laboratory evaluation. A high clinical suspicion in patients with unexplained dyspnea is also required to reach a firm diagnosis. We herein present a rare case of an 82-years-old patient with episodic unexplained dyspnea, patent foramen ovale with normal pulmonary pressures and we review the underlying physiologic mechanisms.

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References

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Published
2021-09-28
Info
Issue
Section
Pneumology - Case Reports
Supporting Agencies
none
Keywords:
Patent foramen ovale, platypnea orthodeoxia syndrome, hypoxemia
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How to Cite
Sampsonas, Fotios, Matthaios Katsaras, Ourania Papaioannou, Theodoros Karampitsakos, Lampros Lakkas, Lampros K. Michalis, and Argyrios Tzouvelekis. 2021. “Platypnea Orthodeoxia Syndrome in a Patient With Patent Foramen Ovale and Normal Atrial Pressure. Case Report and Presentation of Underlying Pathophysiological Mechanisms”. Monaldi Archives for Chest Disease, September. https://doi.org/10.4081/monaldi.2021.1878.