SARS-CoV-2 related pneumonia in an adult with cystic fibrosis: natural favourable clinical course or effective therapy?
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Maddalena Giglia
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maddalena.giglia@studio.unibo.it
Department of Medical and Surgical Sciences, Clinics of Infectious Diseases, S. Orsola-Malpighi Hospital, "Alma Mater Studiorum" University of Bologna, Italy.
https://orcid.org/0000-0002-3838-4041
- Giacomo Beci Department of Medical and Surgical Sciences, Clinics of Infectious Diseases, S. Orsola-Malpighi Hospital, "Alma Mater Studiorum" University of Bologna, Italy. https://orcid.org/0000-0001-8528-3924
- Elena Rosselli Del Turco Department of Medical and Surgical Sciences, Clinics of Infectious Diseases, S. Orsola-Malpighi Hospital, "Alma Mater Studiorum" University of Bologna, Italy. https://orcid.org/0000-0002-9059-4804
- Viola Guardigni Department of Medical and Surgical Sciences, Clinics of Infectious Diseases, S. Orsola-Malpighi Hospital, "Alma Mater Studiorum" University of Bologna, Italy. https://orcid.org/0000-0002-2769-7325
- Alberto Amedeo Department of Medical and Surgical Sciences, Clinics of Infectious Diseases, S. Orsola-Malpighi Hospital, "Alma Mater Studiorum" University of Bologna, Italy. https://orcid.org/0000-0003-3787-0846
- Giulia Cucchetto Cystic Fibrosis Regional Centre, AOUI Verona, Italy.
- Gabriella Verucchi Department of Medical and Surgical Sciences, Clinics of Infectious Diseases, S. Orsola-Malpighi Hospital, "Alma Mater Studiorum" University of Bologna, Italy.
- Marco Cipolli Cystic Fibrosis Regional Centre, AOUI Verona, Italy. https://orcid.org/0000-0001-5652-7248
- Leonardo Calza Department of Medical and Surgical Sciences, Clinics of Infectious Diseases, S. Orsola-Malpighi Hospital, "Alma Mater Studiorum" University of Bologna, Italy.
- Pierluigi Viale Department of Medical and Surgical Sciences, Clinics of Infectious Diseases, S. Orsola-Malpighi Hospital, "Alma Mater Studiorum" University of Bologna, Italy.
Abstract
We report the case of a man affected by cystic fibrosis who developed a severe SARS-CoV-2 related pneumonia in March 2020. In addition to lopinavir/ritonavir and hydroxychloroquine, he was treated with two doses of tocilizumab, displaying a significant clinical improvement. This is the first case described in the literature of an adult patient affected by cystic fibrosis who received tocilizumab for COVID-19, with documented total recovery, also assessed by a spirometry.
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Published
2020-12-23
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Issue
Section
COVID-19 - Collection of articles on the Coronavirus outbreak
Keywords:
COVID-19, tocilizumab, cystic fibrosis
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How to Cite
Giglia, M., Beci, G., Rosselli Del Turco, E., Guardigni, V., Amedeo, A., Cucchetto, G., Verucchi, G., Cipolli, M., Calza, L., & Viale, P. (2020). SARS-CoV-2 related pneumonia in an adult with cystic fibrosis: natural favourable clinical course or effective therapy?. Monaldi Archives for Chest Disease, 90(4). https://doi.org/10.4081/monaldi.2020.1579
Copyright (c) 2020 The Author(s)
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