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15 February 2016
Vol. 65 No. 1 (2006): Pulmonary series
https://doi.org/10.4081/monaldi.2006.587

Lung Stem Cell Update: Promise and Controversy

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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Somatic stem cells, transdifferentiation, embryonic stem cells
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Authors

I.P. Neuringer
randell@med.unc.edu
Division of Pulmonary and Critical Care Medicine; Departments of Medicine and Cellular and Molecular Physiology; The University of North Carolina; Chapel Hill, North Carolina, United States.
S.H. Randell
Division of Pulmonary and Critical Care Medicine; Departments of Medicine and Cellular and Molecular Physiology; The University of North Carolina; Chapel Hill, North Carolina, Italy.
Currently, there is great enthusiasm about potential stem cell therapies for intractable diseases. We previously reviewed the topic of stem cells in lung injury and repair, including the role of endogenous, tissue (somatic) stem cells and the contribution of circulating cells to the lung parenchyma. Our purpose here is to provide a concise update in this fast-moving field. New information and ongoing debate focus attention on basic issues in lung stem cell biology and highlight the need for additional studies to establish the feasibility of cell therapies to prevent or treat lung diseases.

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“Lung Stem Cell Update: Promise and Controversy”. 2016. Monaldi Archives for Chest Disease 65 (1). https://doi.org/10.4081/monaldi.2006.587.