https://doi.org/10.4081/monaldi.2025.3326
Skin prick test wheal size: a potential predictor of respiratory allergies?
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Published: 29 April 2025
Dear Editor,
The skin prick test (SPT) is the most commonly used method for diagnosing IgE-mediated sensitizations in conditions like bronchial asthma, allergic rhinitis, and food allergies...
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Promoted by the Italian Association of Hospital and Territorial Allergists and Immunologists (AAIITO – Campania region).
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Nur Husna SM, Md Shukri N, Tan HT, et al. Higher wheal sizes of Dermatophagoides farina sensitization exhibit worse nasal symptoms in allergic rhinitis patients. Front Med 2022;9:843432. DOI: https://doi.org/10.3389/fmed.2022.843432
Madani S, Zandieh F, Ahmadi M, et al. Does the reaction size of skin prick test associated with the allergic rhinitis symptom severity? Allergol Immunopathol 2021;49:60-2. DOI: https://doi.org/10.15586/aei.v49i6.211
Haahtela T, Burbach GJ, Bachert C, et al. Clinical relevance is associated with allergen-specific wheal size in skin prick testing. Clin Exp Allergy 2014;44:407-16. DOI: https://doi.org/10.1111/cea.12240
Scichilone N, Callari A, Augugliaro G, et al. The impact of age on prevalence of positive skin prick tests and specific IgE tests. Respir Med 2011;105:651-8. DOI: https://doi.org/10.1016/j.rmed.2010.12.014
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CRediT authorship contribution
Gennaro Liccardi: study concept and design, manuscript drafting, literature review. Mauro Maniscalco, Maria Beatrice Bilò, Lorenzo Cecchi, Manlio Milanese, Paola Roglian: manuscript drafting and critical insight. Matteo Martini, Annaclaudia Giordano: statistical analysis. Claudio Candia: manuscript re-editing process. Gennaro Liccardi, Carmen Montera, Fabio De Bartolomeis, Antonio Papa, Domenico Gargano, Mario Lo Schiavo, Francesco Madonna, Alfonso Savoia: skin prick tests and data collection. All the authors critically revised and approved the manuscript.
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