Letters to the Editor
November 4, 2024
Early Access
Novel tuberculosis skin tests for detecting latent tuberculosis infection
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
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Dear Editor,
We are impressed by the article titled “Latent tuberculosis diagnostics: current scenario and review” by Gupta et al. published in your journal. The authors have reviewed the tests used for diagnosis of latent tuberculosis infection and have given a detailed overview of the purified protein derivative-based tuberculin skin test and interferon γ release assays. We would like to draw attention to the fact that in 2022, the World Health Organization has also recommended the use of Mycobacterium tuberculosis antigen-based skin tests for the diagnosis of latent tuberculosis (conditional recommendation, very low certainty of evidence).
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Citations
Gupta A, Chandra E, Anand S, et al. Latent tuberculosis diagnostics: current scenario and review. Monaldi Arch Chest Dis 2024; doi: 10.4081/monaldi.2024.2984. DOI: https://doi.org/10.4081/monaldi.2024.2984
WHO. WHO consolidated guidelines on tuberculosis. Module 3: diagnosis. Tests for TB infection. Available from: https://iris.who.int/bitstream/handle/10665/362936/9789240056084-eng.pdf?sequence=1.
Krutikov M, Faust L, Nikolayevskyy V, et al. The diagnostic performance of novel skin-based in-vivo tests for tuberculosis infection compared with purified protein derivative tuberculin skin tests and blood-based in vitro interferon-γ release assays: a systematic review and meta-analysis. Lancet Infect Dis 2022;22:250-64. DOI: https://doi.org/10.1016/S1473-3099(21)00261-9
Badaro R, Machado BAS, Duthie MS, et al. The single recombinant M. tuberculosis protein DPPD provides enhanced performance of skin testing among HIV-infected tuberculosis patients. AMB Express 2020;10:133. DOI: https://doi.org/10.1186/s13568-020-01068-6
How to Cite
“Novel Tuberculosis Skin Tests for Detecting Latent Tuberculosis Infection”. 2024. Monaldi Archives for Chest Disease, November. https://doi.org/10.4081/monaldi.2024.3156.
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