Paraskeletal plasmacytoma presenting as a chest wall mass

Submitted: May 15, 2023
Accepted: June 29, 2023
Published: July 28, 2023
Abstract Views: 212
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Authors

Extramedullary involvement in multiple myeloma is uncommon. It can present as a plasma cell mass in the soft tissue surrounding the bony structures through direct extension or in various other organs via hematogenous spread. Here, we report a case of paraskeletal plasmacytoma that manifested as a chest wall mass in a 60-year-old man.

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Citations

van de Donk NWCJ, Pawlyn C, Yong KL. Multiple myeloma. Lancet 2021;397:410-27. DOI: https://doi.org/10.1016/S0140-6736(21)00135-5
Rajkumar SV. Multiple myeloma: 2022 update on diagnosis, risk stratification, and management. Am J Hematol 2022;97:1086-107.
Jagosky MH, Usmani SZ. Extramedullary disease in multiple myeloma. Curr Hematol Malig Rep 2020;15:62-71. DOI: https://doi.org/10.1007/s11899-020-00568-3
Varettoni M, Corso A, Pica G, et al. Incidence, presenting features and outcome of extramedullary disease in multiple myeloma: a longitudinal study on 1003 consecutive patients. Ann Oncol 2010;21:325-30. DOI: https://doi.org/10.1093/annonc/mdp329
Weinstock M, Ghobrial IM. Extramedullary multiple myeloma. Leuk Lymphoma 2013;54:1135-41. DOI: https://doi.org/10.3109/10428194.2012.740562
Bladé J, Beksac M, Caers J, et al. Extramedullary disease in multiple myeloma: a systematic literature review. Blood Cancer J 2022;12:45. DOI: https://doi.org/10.1038/s41408-022-00643-3
Rosiñol L, Beksac M, Zamagni E, et al. Expert review on soft-tissue plasmacytomas in multiple myeloma: definition, disease assessment and treatment considerations. Br J Haematol 2021;194:496-507. DOI: https://doi.org/10.1111/bjh.17338
Dimopoulos MA, Hillengass J, Usmani S, et al. Role of magnetic resonance imaging in the management of patients with multiple myeloma: a consensus statement. J Clin Oncol 2015;33:657-64. DOI: https://doi.org/10.1200/JCO.2014.57.9961
Lu YY, Chen JH, Lin WY, et al. FDG-PET or PET/CT for detecting intramedullary and extramedullary lesions in multiple myeloma: a systematic review and metaanalysis. Clin Nucl Med 2012;37:833–7. DOI: https://doi.org/10.1097/RLU.0b013e31825b2071
Hussong JW, Perkins SL, Schnitzer B, et al. Extramedullary plasmacytoma. A form of marginal zone cell lymphoma? Am J Clin Pathol 1999;111:111-6. DOI: https://doi.org/10.1093/ajcp/111.1.111
Saha R, Bhattacharya A, Deb J, et al. Multiple myeloma presenting as thoracic plasmacytoma – two rare cases. Egypt J Chest Dis Tuberc 2014;63:267–71. DOI: https://doi.org/10.1016/j.ejcdt.2013.10.008
Lok R, Golovyan D, Smith J. Multiple myeloma causing interstitial pulmonary infiltrates and soft-tissue plasmacytoma. Respir Med Case Rep 2018;24:155-7. DOI: https://doi.org/10.1016/j.rmcr.2018.05.023
Yuan H, Lei H, Gu P, Ma L, Qiu L. A rare case of extramedullary multiple myeloma presenting as masses on the breast and chest wall complicated with Sjogren's syndrome. Int J Gen Med 2021;14:51-5. DOI: https://doi.org/10.2147/IJGM.S287405
Tazi I, Nafil H, Mahmal L. Chest wall tumor at relapse of multiple myeloma. Afr Health Sci 2013;13:160-1. DOI: https://doi.org/10.4314/ahs.v13i1.22
Rajkumar SV. Multiple myeloma: 2022 update on diagnosis, risk stratification, and management. Am J Hematol 2022;97:1086-107. DOI: https://doi.org/10.1002/ajh.26590
Pour L, Sevcikova S, Greslikova H, et al. Soft-tissue extramedullary multiple myeloma prognosis is significantly worse in comparison to bone-related extramedullary relapse. Haematologica 2014;99:360–4. DOI: https://doi.org/10.3324/haematol.2013.094409
Beksac M, Seval GC, Kanellias N, et al. A real world multicenter retrospective study on extramedullary disease from Balkan Myeloma Study Group and Barcelona University: analysis of parameters that improve outcome. Haematologi-ca 2020;105:201-8. Erratum in: Haematologica 2021;106:1228. DOI: https://doi.org/10.3324/haematol.2019.219295

How to Cite

Mallik, Sonali, Ananda Datta, and Debahuti Mohapatra. 2023. “Paraskeletal Plasmacytoma Presenting As a Chest Wall Mass”. Monaldi Archives for Chest Disease, July. https://doi.org/10.4081/monaldi.2023.2637.