SARS-CoV-2 related pneumonia in an adult with cystic fibrosis: natural favourable clinical course or effective therapy?

Maddalena Giglia; Giacomo Beci; Elena Rosselli Del Turco; Viola Guardigni; Alberto Amedeo; Giulia Cucchetto; Gabriella Verucchi; Marco Cipolli; Leonardo Calza; Pierluigi Viale

doi:10.4081/monaldi.2020.1579

COVID-19 - Collection of articles on the Coronavirus outbreak Open access

SARS-CoV-2 related pneumonia in an adult with cystic fibrosis: natural favourable clinical course or effective therapy?

Authors

Maddalena Giglia – articles in this journal Corresponding author Email https://orcid.org/0000-0002-3838-4041 Department of Medical and Surgical Sciences, Clinics of Infectious Diseases, S. Orsola-Malpighi Hospital, "Alma Mater Studiorum" University of Bologna, Italy.
Giacomo Beci – articles in this journal https://orcid.org/0000-0001-8528-3924 Department of Medical and Surgical Sciences, Clinics of Infectious Diseases, S. Orsola-Malpighi Hospital, "Alma Mater Studiorum" University of Bologna, Italy.
Elena Rosselli Del Turco – articles in this journal https://orcid.org/0000-0002-9059-4804 Department of Medical and Surgical Sciences, Clinics of Infectious Diseases, S. Orsola-Malpighi Hospital, "Alma Mater Studiorum" University of Bologna, Italy.
Viola Guardigni – articles in this journal https://orcid.org/0000-0002-2769-7325 Department of Medical and Surgical Sciences, Clinics of Infectious Diseases, S. Orsola-Malpighi Hospital, "Alma Mater Studiorum" University of Bologna, Italy.
Alberto Amedeo – articles in this journal https://orcid.org/0000-0003-3787-0846 Department of Medical and Surgical Sciences, Clinics of Infectious Diseases, S. Orsola-Malpighi Hospital, "Alma Mater Studiorum" University of Bologna, Italy.
Giulia Cucchetto – articles in this journal Cystic Fibrosis Regional Centre, AOUI Verona, Italy.
Gabriella Verucchi – articles in this journal Department of Medical and Surgical Sciences, Clinics of Infectious Diseases, S. Orsola-Malpighi Hospital, "Alma Mater Studiorum" University of Bologna, Italy.
Marco Cipolli – articles in this journal https://orcid.org/0000-0001-5652-7248 Cystic Fibrosis Regional Centre, AOUI Verona, Italy.
Leonardo Calza – articles in this journal Department of Medical and Surgical Sciences, Clinics of Infectious Diseases, S. Orsola-Malpighi Hospital, "Alma Mater Studiorum" University of Bologna, Italy.
Pierluigi Viale – articles in this journal Department of Medical and Surgical Sciences, Clinics of Infectious Diseases, S. Orsola-Malpighi Hospital, "Alma Mater Studiorum" University of Bologna, Italy.

Published: 23 December 2020
Issue: Vol. 90 No. 4 (2020)
Section: COVID-19 - Collection of articles on the Coronavirus outbreak
DOI: 10.4081/monaldi.2020.1579

Abstract

We report the case of a man affected by cystic fibrosis who developed a severe SARS-CoV-2 related pneumonia in March 2020. In addition to lopinavir/ritonavir and hydroxychloroquine, he was treated with two doses of tocilizumab, displaying a significant clinical improvement. This is the first case described in the literature of an adult patient affected by cystic fibrosis who received tocilizumab for COVID-19, with documented total recovery, also assessed by a spirometry.

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Article history

Received: 20 August 2020
Accepted: 10 November 2020
Published: 23 December 2020

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How to Cite

Giglia, Maddalena, Giacomo Beci, Elena Rosselli Del Turco, Viola Guardigni, Alberto Amedeo, Giulia Cucchetto, Gabriella Verucchi, Marco Cipolli, Leonardo Calza, and Pierluigi Viale. 2020. “SARS-CoV-2 Related Pneumonia in an Adult With Cystic Fibrosis: Natural Favourable Clinical Course or Effective Therapy?”. Monaldi Archives for Chest Disease 90 (4). https://doi.org/10.4081/monaldi.2020.1579.

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