Pulmonary embolism in Behcet’s disease: a case report

Submitted: April 29, 2020
Accepted: September 7, 2020
Published: November 2, 2020
Abstract Views: 871
PDF: 532
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Behcet’s disease (BD) is a vasculitis of unknown etiology. It is often correlated with thrombophilic factors such as V Leiden. Pulmonary involvement is reported in 1-10% of patients. The most common manifestations are pulmonary aneurysms while pulmonary embolism is a rare complication. A 41-year old man with BD and V Leiden heterozygosity complained of pleurodynia and fever. Pleurodynia deteriorated in the following days and PE was confirmed by CT angiography, without the presence of aneurysms. After the exclusion of the antiphospholipid syndrome, a therapeutic dose of apixaban was initiated. Two weeks later, pleurodynia relapsed in combination with pleural effusion unilaterally. These findings were attributed to disease exacerbation. For this reason, we decided to enhance the immunosuppressive therapy. Six months later, CTPA showed complete remission of the clots. Vasculitis predisposes to thrombosis with or without coexisting thrombophilia. Clinicians should include them in their differential diagnosis and provide personalized treatment, based on immunosuppressants.

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Moumtzi, Despoina, and Marianna Kakoura. 2020. “Pulmonary Embolism in Behcet’s Disease: A Case Report”. Monaldi Archives for Chest Disease 90 (4). https://doi.org/10.4081/monaldi.2020.1347.