@article{Jain_Khanna_Sarkar_2021, title={Comparative evaluation of ventilator-associated pneumonia in critically ill COVID- 19 and patients infected with other corona viruses: a systematic review and meta-analysis}, volume={92}, url={https://www.monaldi-archives.org/macd/article/view/1610}, DOI={10.4081/monaldi.2021.1610}, abstractNote={<p style="margin: 0cm; text-align: justify;"><span lang="EN-IN" style="color: #0e101a;">The Coronavirus disease 19 (COVID-19) pandemic is associated with an unprecedented requirement for intensive care unit (ICU) admission, invasive mechanical ventilation, and thereby significantly increasing the risk of secondary nosocomial pneumonia, ventilator-associated pneumonia (VAP). </span><span lang="EN-IN" style="color: #0e101a;">Our study aims to identify the overall incidence of VAP, common organisms associated with it, and outcome in COVID-19 patients in comparison to the non-SARS-CoV-2 infected critically ill ventilated COVID-19 patients. A comprehensive screening was conducted using major electronic databases), from January 1<sup>st</sup> 2020 to May 31<sup>st</sup> 2021, as per the PRISMA statement. In our rapid review, we included a total of 34 studies (involving 8901 cases. Overall VAP was reported in 48.15 % (95% CI 42.3%-54%) mechanically ventilated COVID-19 patients and the mortality rate was 51.4% (95% CI 42.5%-60%). COVID-19 patients had increased risk of VAP and mortality in comparison to other non-SARS-CoV-2 viral pneumonia (OR=2.33; 95%CI 1.75-3.11; I<sup>2</sup>=15%, and OR=1.46; 95%CI 1.15-1.86; I<sup>2</sup>=0% respectively). Critically ill COVID-19 patients are prone to develop VAP, which worsens the outcome.</span></p>}, number={2}, journal={Monaldi Archives for Chest Disease}, author={Jain, Shikha and Khanna, Puneet and Sarkar, Soumya}, year={2021}, month={Sep.} }