Obesity and metabolic syndrome: clinical and therapeutic review

Submitted: February 17, 2016
Accepted: February 17, 2016
Published: March 30, 2005
Abstract Views: 1834
PDF: 1310
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The recent ATP III classification defines metabolic syndrome as including ≥3 of the following characteristics: abdominal adiposity, atherogenic dyslipidemia, high blood pressure, and insulin resistance. In these patients the visceral fat may produce inflammatory cytochines that may account for an enhanced cardiovascular risk. The treatment of obese patients is complex and often ineffective: patients may initially reduce weight but subsequently regain or even increase it, according to the socalled “yo-yo syndromeâ€. Given the difficulties of treatment of patients with incresed BMI, visceral adiposity, or metabolic syndrome, a multidisciplinary approach to these patients may yield more frequent positive results. The different strategies that may be applied, in varying mix targeted to the individual patient, include diet, drugs, educational and psychological support and, in few selected cases, surgery.

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Cuppini, Andrea, and Paola Matteini. 2005. “Obesity and Metabolic Syndrome: Clinical and Therapeutic Review”. Monaldi Archives for Chest Disease 64 (1). https://doi.org/10.4081/monaldi.2005.612.

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